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Image
Caption A: A mutant allele yielding geranylgeranylated progerin, Lmnatm4Lgf (LmnaggHG), was generated with a sequence-replacement vector that removes intron 10, intron 11, and the last 150 bp of exon 11, and introduces a point mutation in exon 12 that changes the methionine in the CaaX motif to leucine.
Copyright This image is from Davies BS, J Lipid Res 2009 Jan;50(1):126-34 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text is from JLR. J:146099
Associated
Alleles
Symbol Name
Lmnatm4Lgf lamin A; targeted mutation 4, Loren G Fong

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory