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| Caption | Generation of the Msrb1Gt(OST336894)Lex gene-trapped allele. A, mouse Msrb1 gene and its flanking regions. The upper part of the panel shows the Msrb1 gene and its flanking genes, and the lower part illustrates Msrb1 exons (in red) and repetitive elements (in blue). The targeting strategy is also shown wherein a Neo cassette (in green) replaces the first exon using the areas of homologous recombination (in gray). Two alternative 3' arms of the targeting construct are indicated (dashed line). B, the genetrap construct. The trapping cassette was inserted immediately downstream of the first exon. Locations of Msrb1 exons (in orange), Sec (shown as a red U), and the Sec insertion sequence (in blue) are also indicated. | ||||
| Copyright | This image is from Fomenko DE, J Biol Chem 2009 Feb 27;284(9):5986-93 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:147916 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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