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Molecular Image Detail
Image
Caption A, diagrams of the Smad7 protein, the exon-intron structure of mouse Smad7 gene, the knockout construct, and the outcomes of homologous recombination. Smad7loxP refers to the Smad7tm1Shou allele and Smad7deltaMH2 refers to the Smad7tm1.1Shou allele. The numbering of amino acid is illustrated at the top. The position of the genomic region used for Southern blotting analysis is labeled with a bold bar. E stands for exons and H for HindIII restriction sites. The translation initiation site is marked as ^, and the stop codon is marked as *.
Copyright This image is from Chen Q, J Biol Chem 2009 Jan 2;284(1):292-300 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:145777
Associated
Alleles
Symbol Name
Smad7tm1.1Shou SMAD family member 7; targeted mutation 1.1, Weinian Shou
Smad7tm1Shou SMAD family member 7; targeted mutation 1, Weinian Shou

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory