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| Caption | Conditional Chr 13 Prelid1 gene targeting. (a) Overall Schema I; wild-type allele depicts Prelid1 (PRELI) gene flanked by Rab24 (left) and Mxd3 (Mad3, right) genes; II: Targeting vector construct displays relevant restrictions sites (Asc1 [A], BamH1 [B], Cla1 [C], EcoR1 [R1], Not1 [N], Pme1 [P], Sal1 [S], and Xba1 [X]). Also indicated are 5' and 3' arms of homology, LoxP sites, Flip recombination (Frt) sequences, and PGK-Neo and HSV-Tk selection cassettes; III: Floxed Prelid1tm1Hmva allele; after Frt-mediated removal of selection cassettes; IV: Prelid1 deficient allele after Cre recombinase (Cre) cleavage of Prelid1 exon II. Location of 5' and 3' external probes used in Southern Blot hybridization experiments is indicated. | ||||
| Copyright | This image is from Ma W, PLoS One 2012;7(5):e37949, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:187294 | ||||
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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