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| Caption | Generation of the floxed Nr0b2tm1Mjev (Floxed SHP allele) and deleted Nr0b2tm1.1Mjev (Deleted SHP allele) alleles. The top line shows a diagram of the wild-type allele with the coding exons denoted by filled boxes. Exon 1 contains the translation start site. The second line diagrams a successfully targeted conditional deletion allele in which LoxP sites (open triangles) have been inserted flanking the Nr0b2 exon 1 by the use of a neomycin resistance gene (Neor) driven by the phosphoglycerate kinase promoter (PGK). The bottom line depicts the deleted Nr0b2 allele resulting from breeding with transgenic mice expressing Cre recombinase. The positions of the primers F1, R1, and R2 used for genotyping mice are shown by arrows. | ||||||
| Copyright | This image is from Hartman HB, J Lipid Res 2009 Feb;50(2):193-203 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text is from JLR. J:149005 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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