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Molecular Image Detail
Image
Caption Schematic of the ENU-induced Mycbp2m274-4Tpo mutation. (a) Multiple conserved domains (Uni-ProtKB/Swiss-Prot) contained in the protein encoded by the Mycbp2 locus include lysine (Lys), cysteine (Cys), serine (Ser), proline (Pro), and glycine (Gly) rich amino acid regions, five regulators of chromosome condensation (RCC1) homology repeats, a filamin repeat, DOC domain, RING-type zinc finger (RZF), and B box-type zinc finger BbZF. Sequence analysis of transcripts produced by mutants revealed a T to A transversion at nucleotide position 2,599 within exon 15 of the 85 exon Mycbp2 gene.
Copyright This image is from Hagarman JA, Genesis 2009 Jun;47(6):392-403, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:149893
Associated
Alleles
Symbol Name
Mycbp2m274-4Tpo MYC binding protein 2, E3 ubiquitin protein ligase; mutation 274-4, Timothy P O'Brien

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory