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Molecular Image Detail
Image
Caption Schematic representation of the generation of conditional Mir122tm1.2Kgh (miR-122floxed) and germline Mir122tm1.1Kgh (miR-122delta) alleles. The targeting vector was generated by amplifying homology arms from 129 genomic DNA, which were cloned into pBSK. Targeted mouse ES cell clones and chimeric mice were generated at the University of Michigan Knockout Mouse Core Facility. Two independent targeted clones were transmitted through the mouse germ line.
Copyright This image is from Hsu SH, J Clin Invest 2012 Aug 1;122(8):2871-83 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:190067
Associated
Alleles
Symbol Name
Mir122tm1.1Kgh microRNA 122; targeted mutation 1.1, Kalpana Ghoshal
Mir122tm1.2Kgh microRNA 122; targeted mutation 1.2, Kalpana Ghoshal

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory