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Caption | Schematic representation of the generation of conditional Mir122tm1.2Kgh (miR-122floxed) and germline Mir122tm1.1Kgh (miR-122delta) alleles. The targeting vector was generated by amplifying homology arms from 129 genomic DNA, which were cloned into pBSK. Targeted mouse ES cell clones and chimeric mice were generated at the University of Michigan Knockout Mouse Core Facility. Two independent targeted clones were transmitted through the mouse germ line. | ||||||
Copyright | This image is from Hsu SH, J Clin Invest 2012 Aug 1;122(8):2871-83 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:190067 | ||||||
Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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