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| Caption | (A) Targeting strategy. The wild-type locus spanning the coding region (18.2 kb) is depicted (top). The targeting vector was constructed using Mybbp1a 5' genomic sequences (3.5 kb) and 3' sequences (6.0 kb) flanking a pgkNEO expression cassette (1.8 kb) as shown. The targeted allele, Mybbp1atm1Fbla maintains the 3' region, but removes 5' region including the initiation codon (ATG) and exons 1-13, as depicted (bottom). Non-coding sequences are shown as thick black lines, exons are black boxes and restriction enzyme sites are indicated as H, HindIII, and X, XbaI. | ||||
| Copyright | This image is from Mori S, PLoS One 2012;7(10):e39723, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:191942 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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