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Caption | Generation of the Trim50tm1Hta allele. (A) Homologous recombination at the Trim50 locus. The restriction enzyme maps of the wild-type allele, targeting vector, and mutant allele are illustrated. The first exon, the second exon, the neomycin-resistance gene (neo), and the diphtheria toxin gene (DTA) are indicated by boxes; the direction of transcription is shown by arrows. The hybridization probe for Southern blot screening and primers for PCR genotyping are indicated by a hatched box and open arrows, respectively. | ||||
Copyright | This image is from Nishi M, J Biol Chem 2012 Sep 28;287(40):33523-32 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:191586 | ||||
Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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