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| Caption | (A) Schematic diagrams of the wild-type (WT) and knockout (KO) Atf5tm1Mrgr alleles. To generate the KO allele, a LacZ-Neo cassette was inserted in frame and replaced most of exon 1 (E1) and all of exons 2 and 3 (E2 and E3, respectively). The gene replacement results in an increase in length of a KpnI restriction fragment that encompasses the Atf5 locus from 5.7 kb (WT allele) to 9.3 kb (KO allele). K represents the KpnI sites; ATG represents the translation start site; bZIP denotes the basic region leucine zipper domain. | ||||
| Copyright | This image is from Wang SZ, Proc Natl Acad Sci U S A 2012 Nov 6;109(45):18589-94. Copyright 2012 National Academy of Sciences, U.S.A. J:191236 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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