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| Caption | Generation of the Sumo1tm1.1Bros allele. (A) Structure of the Sumo1 gene, targeting vector, mutated gene after homologous recombination, and mutated gene after homologous recombination and Cre recombination to remove the Neo and generate the Sumo1tm1.1Bros allele. The first coding exon is indicated by a black box, and an asterisk marks the insertion of the His6-HA tag, whose coding sequence and insertion location are shown beneath the targeting vector. loxP sites are indicated by triangles. The probe used for Southern blot analysis and the PCR primers used for genotyping are shown below the structure of the mutated and Cre recombined gene. Neo, neomycin resistance gene; TK, herpes simplex virus thymidine kinase. | ||||
| Copyright | This image is from Tirard M, Proc Natl Acad Sci U S A 2012 Dec 18;109(51):21122-7. Copyright 2012 National Academy of Sciences, U.S.A. J:193101 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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