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| Caption | (A) Targeting strategy to generate the Il2rgtm1.1Asin (Ycfl) allele. Numbered boxes = exons, gray boxes = out of frame exons as a result of Cre-mediated deletion. NeoR = neomycin resistance cassette. Black triangles = loxP sites. Gray ovals = frt sites. K, S = Kpn1 and Sac1 restriction sites, respectively. Locations of PCR primers are indicated with facing arrows. Location of 3' probe for Southern blot is indicated. Cre-mediated recombination can be used to conditionally delete exons 2-6 (gammacdelta) of Il2rg. | ||||
| Copyright | This image is from McCaughtry TM, J Exp Med 2012 Nov 19;209(12):2263-76, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:190889 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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