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Molecular Image Detail
Image
Caption Generation of the Cited2tm3.1Bha (Cited2T166) allele. (A) Targeting strategy by homologous recombination. The T to N change was introduced by site directed mutagenesis into the orthologous residue in the mouse sequence. The structure of the wild-type allele, targeting vector, targeted allele, and its structure after FLP mediated recombination are shown. The open reading frame (ORF, blue arrow) is entirely contained within exon 2 (exons indicated by grey rectangles). The targeting vector has an frt-PGK-NeoR-frt selection cassette downstream of exon 2 followed by a DTA (diphtheria toxin) cassette.
Copyright This image is from Chen CM, PLoS One 2012;7(10):e46256, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:192202
Associated
Alleles
Symbol Name
Cited2tm3.1Bha Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; q targeted mutation 3.1, Shoumo Bhattacharya
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory