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Caption | Generation of the Cited2tm6Bha (Cited2HUM) allele. The human full length CITED2 was targeted into the Cited2 locus via PhiC31 integrase mediated cassette exchange. The exchange event occurs between the attP and attB sites giving rise to attL and attR sites. Successful exchange replaces the mouse Cited2 open reading frame (ORF) with that of the full length human CITED2 and brings the puromycin resistance gene under control of the PGK promoter. | ||||
Copyright | This image is from Chen CM, PLoS One 2012;7(10):e46256, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:192202 | ||||
Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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