About   Help   FAQ
Molecular Image Detail
Image
Caption Generation of the Tdgtm1Psch allele. Gene Targeting of Tdg on Chromosome 10. The targeting construct was generated by replacement of exons 6 and 7 with a neomycin resistance cassette. This was achieved by the substitution of a NarI-PacI fragment with the resistance cassette in a subcloned genomic region spanning from intron 4 to the 3' UTR. In addition, the targeting construct contained a thymidine kinase (TK) cassette for negative selection. Arrowheads show the position of primers used for multiplex-PCR genotyping. The expected length of PCR products are 1.2 kb and 1.5 kb for the wild-type (wt) and the targeted loci, respectively.
Copyright This image is from Kunz C, PLoS Biol 2009 Apr 28;7(4):e91, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:196431
Associated
Alleles
Symbol Name
Tdgtm1Psch thymine DNA glycosylase; targeted mutation 1, Primo Schar

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory