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Molecular Image Detail
Image
Caption Diagram showing structure of the wild-type Lmx1a gene, and the Lmx1amtl (mtl) and Lmx1absd (bsd) spontanous mutations. Initiation codon in exon 1 and termination codon in exon 8 are indicated. Point mutation in mtl homozygotes is indicated by a red asterisk and deletion in bsd mutants is shown by a red dotted line. Mtl mutation affects the homeodomain whereas in bsd, the deletion of exon 3 involves the LIM2 domain.
Copyright This image is from Steffes G, PLoS One 2012;7(11):e51065, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:194385
Associated
Alleles
Symbol Name
Lmx1absd LIM homeobox transcription factor 1 alpha; belly spot and deafness
Lmx1amtl LIM homeobox transcription factor 1 alpha; mutanlallemand

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory