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| Caption | Generation of the dual affinity tagged Rb1tm2.1Dwg allele in the mouse. (A) A schematic representation of the exon/intron structure of the targeted region of the Rb1 gene, the targeting vector, and the expected structure of the successfully targeted allele. Exons are numbered and shown as solid boxes. The asterisks and white space shows the position of the dual affinity tag and stop codon. The open boxes represent the neomycin selection cassette and the pBSK cloning vector. LoxP sites are represented by arrowheads. The position of the BgIII (B) restriction enzyme sites and the expected sizes of fragments detected by Southern blotting using a 5' flanking probe are indicated. | ||||
| Copyright | This image is from Xiao H, Genesis 2010 Feb;48(2):121-6, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:158408 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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