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Image
Caption Schematic diagram of the Tg(Pax6-HRAS*G12V)2044Ove transgene. A human H-Ras (G12V) genomic clone (~3.1 Kb) was inserted between a modified Pax6 promoter/enhancer (2.3 Kb) and an intron and polyadenylation (polyA) sequence derived from the SV40 virus (850 bp). The lens/cornea enhancer is contained between the BglII/AccI sites (clear box). The SV40 polyA sequences were used to make riboprobes for detection of transgene expression.
Copyright This image is from Burgess D, BMC Dev Biol 2010;10():13, an open-access article, licensee BioMed Central Ltd. J:158529
Associated
Alleles
Symbol Name
Tg(Pax6-HRAS*G12V)2044Ove transgene insertion 2044, Paul A Overbeek

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory