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| Caption | Generation of the Igf2rtm1.1(IGF2R)Arte allele. Schematic diagram of Igf2r humanisation targeting strategy. Exons are represented as numbered boxes, loxP sites as small triangles, FRT sites as large triangles, human IGF2R mini-gene (Exons 3-48) asopen box, mouse 3' UTR as crossed box. WT, wild type; TV, targeting vector; TA, targeted allele; HA, humanised allele; P, PspOMI; N, NsiI; O1, oligo 1; O2, oligo 2; O3, oligo 3; O4, oligo 4. | ||||
| Copyright | This image is from Hughes J, PLoS One 2013;8(2):e57270, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:197171 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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