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Molecular Image Detail
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Caption (A) Targeting construct used to generate H2-Ab1b-tm1.1Jssh (MHCII (K > R) KI mice. Numbered rectangles indicate exons. The loxP (black arrowhead)-flanked neomycin (neo) cassette was inserted for positive selection of transfected ES cells and the thymidine kinase (TK) cassette was inserted for negative selection. Exon 4 was modified to change the cytoplasmic lysine to an arginine (*).
Copyright This image is from Oh J, J Exp Med 2013 Jun 3;210(6):1069-77, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:201198
Associated
Alleles
Symbol Name
H2-Ab1b-tm1.1Jssh histocompatibility 2, class II antigen A, beta 1; targeted mutation 1.1, Jeoung-Sook Shin

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory