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| Caption | Generation of the Slc4a8tm1.1Doel allele. Targeting of the Slc4a8 locus. The partial genomic structure of the Slc4a8 gene is shown in the upper panel. The middle panel displays the targeted Slc4a8 locus. A neomycin selection cassette flanked by loxP sites (grey arrows) was inserted into intron 11. A third loxP site was introduced into intron 12. Two correctly targeted ES cell clones were transiently transfected with a Cre-recombinase expression plasmid. ES cell clones with a Cre-mediated excision of the DNA fragment between the outer loxP sites (lower panel) were subsequently used for the generation of chimeric mice. | ||||
| Copyright | This image is from Leviel F, J Clin Invest 2010 May 3;120(5):1627-35 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:161474 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/15/2024 MGI 6.24 |
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