Molecular Image Detail

Image

Caption

TALEN mediated recombination scheme used to generate the Zic2^em1Bend, Zic2^em2Bend, Zic2^em3Bend, Zic2^em4Bend and Zic2^em5Bend alleles. Zic2 genomic structure and TALEN binding sites. (A) Genomic structure of the murine Zic2 (upper panel) with an enlargement of exon 2 (lower panel), showing the binding sites of the two monomers for TALEN-A and TALEN-B together with the binding sites of the PCR primers, Zic2-F and Zic2-R used to genotype the mutant alleles.

This image is from Davies B, PLoS One 2013;8(3):e60216, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199882

Associated
Alleles

Symbol	Name
Zic2^em1Bend	zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 1, Ben Davies
Zic2^em2Bend	zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 2, Ben Davies
Zic2^em3Bend	zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 3, Ben Davies
Zic2^em4Bend	zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 4, Ben Davies
Zic2^em5Bend	zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 5, Ben Davies

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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