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Molecular Image Detail
Image
Caption Generation of the Ano1tm1.1Cahb and Ano1tm1.2Cahb alleles. (A) In the targeted Ano1 (Tmem16a) locus, exon 21 is flanked by loxP sites (Ano1tm1.1Cahb, upper panel). After Cre-mediated excision, the floxed fragment is removed (Ano1tm1.2Cahb, lower). Numbered black squares represent exons and triangles, loxP sites; EcoRI restriction sites used for cloning/screening are indicated.
Copyright This image is from Heinze C, J Clin Invest 2014 Feb 3;124(2):675-86 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:207993
Associated
Alleles
Symbol Name
Ano1tm1.1Cahb anoctamin 1, calcium activated chloride channel; targeted mutation 1.1, Christian Hubner
Ano1tm1.2Cahb anoctamin 1, calcium activated chloride channel; targeted mutation 1.2, Christian Hubner

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory