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Caption Targeted vector for the production of the P3h2tm1Hpb allele. The mouse P3h2 (Leprel1) gene spanning 15 exons is schematically presented. A targeted disruption containing a neo cassette (NEO) was made in exon 2 of the gene. A 9-kb Bsa1 restriction fragment spanning exon 2, part of intron 1-2, and most of intron 2-3 was subcloned into a p26 vector, and the neo cassette was cloned within the exon 2 sequence using the AvaI restriction site.
Copyright This image is from Pokidysheva E, Proc Natl Acad Sci U S A 2014 Jan 7;111(1):161-6. Copyright 2014 National Academy of Sciences, U.S.A. J:206377
Associated
Alleles
Symbol Name
P3h2tm1Hpb prolyl 3-hydroxylase 2; targeted mutation 1, Hans Peter Bachinger

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory