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| Caption | Generation of Dhrs3tm1(NCOM)Mfgc allele. A, a diagram showing the wild-type (WT) and mutant knock-out (KO) Dhrs3 alleles. Exons (black boxes) are labeled E1 through E6. Targeting homology is represented by gray boxes. In the mutant allele, a 6001-bp fragment, which contains coding exons E2-E5, is substituted with the 8540-bp NorCOMM targeting cassette. Arrows indicate the location and orientation of genotyping primers (WT-F, WT-R, and KO-R), and long range PCR primers (N01359-s1, GH717, KO-F, and 3' flankR). | ||||||
| Copyright | This image is from Adams MK, J Biol Chem 2014 May 23;289(21):14868-80 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:214109 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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