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| Caption | Generation of the Stra6tm2.1Nbg (L2 allele) and Stra6tm1Nbg (L- allele) alleles. Targeted disruption of the Stra6 gene. A, structure of the targeting vector and partial restriction maps of the wild-type Stra6 locus before ((+) allele) and after (L3 allele) homologous recombination, as well as after FLPe- and Cre-mediated excision (L2 and L- alleles, respectively). Numbered black boxes indicate exons. The locations of restriction sites (A, AijI; B, BclI; X, XbaI) are indicated. Arrowhead flags represent loxP sites; neo, FRT-flanked neomycin resistance cassette. Arrows indicate the location and orientation of PCR primers 1-3. | ||||||
| Copyright | This image is from Berry DC, J Biol Chem 2013 Aug 23;288(34):24528-39 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:203449 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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