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| Caption | Generation of the Ptbp1tm1Msol allele. A) The wild-type locus (blue) was modified with the insertion of a stop/detection cassette (red) into embryonic stem cells. The cassette can be flipped out using an FLP recombinase construct or strain. In addition, exons 3 to 7 have been framed with loxP sites for conditional removal by a Cre recombinase. The diagram indicates the Southern strategy as well as the location of the primers for validation of the construct and genotyping. | ||||
| Copyright | This image is from Suckale J, PLoS One 2011;6(2):e16992, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:223915 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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