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Molecular Image Detail
Image
Caption Targeting strategy for generation of the Kittm1.1Gnf allele. A targeting construct introduced a C to T point mutation in exon 14 that results in the amino acid substitution of isoleucine for threonine at position 670 (T607I). Flp-mediated recombination removed an FRT-flanked neomycin resistance cassette with a 3' loxP site introduced downstream of the modified exon 14.
Copyright This image is from Lau J, PLoS One 2014;9(1):e84900, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:211930
Associated
Alleles
Symbol Name
Kittm1.1Gnf KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1.1, Genomics Institute of the Novartis Research Foundation

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory