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| Caption | Generation of the Gng5tm1.1Rbs (Gng5del) allele. A. Wild type allele (top bar) illustrating the three Gng5 exons (black boxes), homology arms of the targeting vector (grey boxes) and 5' and 3' probes for Southern blotting (striped boxes). Floxed allele (middle bar) illustrating insertion of loxP sites (triangles) and neomycin resistance cassette (NeoR). Deleted allele (bottom bar) illustrating deletion of sequence between 1st and 3rd loxP site including the first exon of Gng5 and NeoR cassette. Also illustrated are expected sizes of fragments following digestion with BamHI (B) or XhoI (X), along with the primers used for PCR (a,b,c). | ||||
| Copyright | This image is from Moon AM, PLoS One 2014;9(3):e90970, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:215128 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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