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| Caption | Generation of the Eomestm1.1Twa allele. (A) Outline of the Eomes-locus (1) and of the insertion. A modifying vector (2) was used to insert an ires-GFP cassette, followed by a Neo selection loxP-flanked cassette auto-excisable in males downstream the Eomes STOP codon (3). After Cre-induced recombination, the Neo cassette is removed, leaving only the ires-GFP and generating the Eomestm1.1Twa allele (4). Different DNA probes (shown in red) were used to check for correct recombination in ES cells by Southern blotting after BAMHI (B) digestion. | ||||
| Copyright | This image is from Daussy C, J Exp Med 2014 Mar 10;211(3):563-77, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:210160 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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