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Caption Generation of the Eomestm1.1Twa allele. (A) Outline of the Eomes-locus (1) and of the insertion. A modifying vector (2) was used to insert an ires-GFP cassette, followed by a Neo selection loxP-flanked cassette auto-excisable in males downstream the Eomes STOP codon (3). After Cre-induced recombination, the Neo cassette is removed, leaving only the ires-GFP and generating the Eomestm1.1Twa allele (4). Different DNA probes (shown in red) were used to check for correct recombination in ES cells by Southern blotting after BAMHI (B) digestion.
Copyright This image is from Daussy C, J Exp Med 2014 Mar 10;211(3):563-77, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:210160
Associated
Alleles
Symbol Name
Eomestm1.1Twa eomesodermin; targeted mutation 1.1, Thierry Walzer

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory