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| Caption | Generation of the Ddhd1tm1Katn and Ddhd1tm1.1Katn alleles. A, schematic representation of the wild-type (+), targeted (geo) Ddhd1tm1Katn, and Ddhd1tm1.1Katn knock-out alleles. The lipase consensus sequence SHSLG is encoded in exon 10. Cre-mediated deletion of exon 8 is supposed to cause a frameshift. Exons of the Ddhd1 gene and loxP sequences are indicated by black boxes and closed triangles, respectively. FRT, Flp recombination target; SA, splice acceptor sequence of mouse engrailed 2; LacZ, Beta-galactosidase gene; Neor, neomycin resistance gene; pA, SV40 polyadenylation signal. | ||||||
| Copyright | This image is from Baba T, J Biol Chem 2014 Apr 18;289(16):11497-511 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:212425 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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