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Caption | Schematic representation of the gene targeting strategy for generating the Ccdc3tm1Ish allele. Partial restriction map of the mouse Ccdc3 (Favine) locus for wild-type allele (top panel). Targeting construct was generated by replacing the regions of exons 1 and 2 containing the translation initiation site ATG and parts of intron 1 with the Neo cassette (middle panel). Transcriptional direction of the Neo gene is indicated by the arrow. Expected disrupted allele was obtained by homologous recombination (bottom panel). | ||||
Copyright | This image is from Kobayashi S, J Biol Chem 2015 Mar 20;290(12):7443-51 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:220560 | ||||
Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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