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Caption Schematic representation of the gene targeting strategy for generating the Ccdc3tm1Ish allele. Partial restriction map of the mouse Ccdc3 (Favine) locus for wild-type allele (top panel). Targeting construct was generated by replacing the regions of exons 1 and 2 containing the translation initiation site ATG and parts of intron 1 with the Neo cassette (middle panel). Transcriptional direction of the Neo gene is indicated by the arrow. Expected disrupted allele was obtained by homologous recombination (bottom panel).
Copyright This image is from Kobayashi S, J Biol Chem 2015 Mar 20;290(12):7443-51 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:220560
Associated
Alleles
Symbol Name
Ccdc3tm1Ish coiled-coil domain containing 3; targeted mutation 1, Iichiro Shimomura

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory