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| Caption | Generation of the conditional Bmal1tm2Bra (Bmal1fx) allele. Schematic diagram illustrating the region surrounding the bHLH domain of the murine Arntl locus. The targeted floxed with neo-in allele (Bmal1fxneo), the conditional floxed allele (Bmal1fx), and the cre-excised allele are shown below the genomic DNA. Exon numbers reflect known coding exons. The positions of the inserted neomycin gene with Frt sites ("down arrowhead") and loxP sites ("left arrowhead") flanking exon 4 are shown. Dotted lines indicate fragment sizes detected by the probe after digestion of genomic DNA with EcoRI. Oligonucleotides (OL) used for genotyping are indicated. | ||||
| Copyright | This image is from Johnson BP, Proc Natl Acad Sci U S A 2014 Dec 30;111(52):18757-62. Copyright 2014 National Academy of Sciences, U.S.A. J:216930 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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