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Caption Targeting strategy for theSox17tm1(icre)Heli allele. A targeting vector was used to introduce icre into exon 1 of the Sox17 gene and the selection cassette was removed by Flp-mediated excision. Sox17 exons (black boxes) are numbered. Promoter regions (yellow boxes) and the two transcriptional starts (red boxes) are indicated. Primers used for genotyping are designated EP418, EP419, and EP510. The external 5' probe is as indicated on the figure. Restriction enzyme sites for EcoRV are shown. Homology regions to generate the targeting constructs are indicated as 5' and 3' retrieval.
Copyright This image is from Liao WP, Genesis 2009 Jul;47(7):476-83, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:150862
Associated
Alleles
Symbol Name
Sox17tm1(icre)Heli SRY (sex determining region Y)-box 17; targeted mutation 1, Heiko Lickert

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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory