| Image |
|
||||
| Caption | Generation of the Decr1tm1Jkh allele. (A) Schematic drawing of the targeting strategy showing the wild type allele, targeting vector and targeted allele after homologous recombination. The targeted allele depicts the strategy used to delete exon 1, in which the endogenous sequence is replaced by a neomycin-positive selection cassette (neo). A thymidine kinase cassette (tk) was used for negative selection. Exons are denoted as numbered solid bars (1-9). Recognition sites for restriction endonucleases are marked as B = BamHI, H = HindIII, E = EcoRI, S = SmalI, EV = EcoRV. The genomic fragment used as an external probe for Southern analysis is marked with an X, and the expected fragments for the WT and targeted allele after BamHI digestion are indicated with arrows. | ||||
| Copyright | This image is from Miinalainen IJ, PLoS Genet 2009 Jul;5(7):e1000543, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:151622 | ||||
|
Associated Alleles |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/10/2024 MGI 6.24 |
|
|
|
||
Analysis Tools