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Caption (A) Schematic diagram of the N3IC targeting vector used for the generation of knockin Gt(ROSA)26Sortm1(Notch3*)Sfr (R26-N3ICSAT) mice. The intracellular domain of the Notch3 receptor (N3IC) was knocked into the ROSA26 locus followed by an internal ribosome entry site and a YFP gene. A lox-STOP-lox cassette blocks the expression of the transgene in the absence of Cre recombinase.
Copyright This image is from Lafkas D, J Cell Biol 2013 Oct 14;203(1):47-56, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:201985
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Gt(ROSA)26Sortm1(Notch3*)Sfr gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Silvia Fre

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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory