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| Caption | Generation of the Fgfrl1tm2.1True allele. Construct and targeted genomic DNA before and after homologous recombination. The region of exon 7, which codes for the dipeptide sequence, the two YXXW motifs and the histidine-rich sequence (amino acid residues 441-529), was replaced by an in-frame GFP sequence. An FLP-flanked neo cassette was inserted downstream of the FgfrL1 gene to enable selection of positive clones by G418. This cassette was subsequently removed by mating with FLP-mice. Kinked arrows show the translation initiation sites of FgfrL1 and Neo, respectively. Arrowheads show the relative position of primers used for genotyping. The sketch is not drawn to scale. | ||||
| Copyright | This image is from Bluteau G, PLoS One 2014;9(8):e105210, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:218981 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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