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| Caption | Generation of the Airetm3(cre)Mmat allele. Targeted insertion of the Cre recombinase gene into the Aire gene locus by homologous recombination. Note that the neor gene cassette in the targeted allele was deleted in mice, probably as a result of autonomous expression of the Aire/Cre gene during early embryogenesis and/or spermatogenesis. (C) Spontaneous deletion of the neor gene cassette in the Aire/Cre-KI line. Primers were designed to detect the presence or absence of the neor gene cassette. | ||||
| Copyright | This image is from Nishikawa Y, J Exp Med 2010 May 10;207(5):963-71, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:160217 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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