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Caption | Generation of the Stard4tm1.1Bres and Stard4tm1.2Bres alleles. A) Targeting strategy employed to insert loxP sites on either side of exon 3 of Stard4. First, a targeting vector was constructed by placing a Neo selectable marker flanked by Frt sites with a loxP site in intron 3. Second, the targeted allele was created by introducing a second loxP in intron 2. Third, crossing the targeted allele mouse to the ACT-FLPe mouse generated the floxed allele (Stard4tm1.1Bres) which was used for all subsequent crosses. Finally, to generate the null allele (Stard4tm1.2Bres), floxed mice were crossed to the CMV-Cre transgenic mice. | ||||||
Copyright | This image is from Riegelhaupt JJ, J Lipid Res 2010 May;51(5):1134-43 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text is from JLR. J:160807 | ||||||
Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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