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Caption | Generation of the Cep290tm1.1Rwjc and Cep290tm2.1Rwjc alleles. Two mouse models were generated by introducing human exons 26 and 27 and intron 26, either with (Cep290tm2.1Rwjc) or without (Cep290tm1.1Rwjc) the LCA-causing mutation (depicted with *), to the mouse Cep290 gene. Human and mouse loci, targeting vector and recombinantlocus are depicted. Arrows and letters indicate the position of the oligonucleotides (see Table S1). | ||||||
Copyright | This image is from Garanto A, PLoS One 2013;8(11):e79369, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:209218 | ||||||
Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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