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Molecular Image Detail
Image
Caption Generation of the Cep290tm1.1Rwjc and Cep290tm2.1Rwjc alleles. Two mouse models were generated by introducing human exons 26 and 27 and intron 26, either with (Cep290tm2.1Rwjc) or without (Cep290tm1.1Rwjc) the LCA-causing mutation (depicted with *), to the mouse Cep290 gene. Human and mouse loci, targeting vector and recombinantlocus are depicted. Arrows and letters indicate the position of the oligonucleotides (see Table S1).
Copyright This image is from Garanto A, PLoS One 2013;8(11):e79369, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:209218
Associated
Alleles
Symbol Name
Cep290tm1.1Rwjc centrosomal protein 290; targeted mutation 1.1, Robert WJ Collin
Cep290tm2.1Rwjc centrosomal protein 290; targeted mutation 2.1, Robert WJ Collin

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory