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| Caption | Generation of the Ghrtm1.1Masp and Ghrtm1.2Masp alleles. A, schematic view of the mouse Ghr gene. The targeting vector contains two engineered loxp sites, flanking exon 4, as well as an frt-tagged neo cassette for positive selection. Light blue boxes: exons. B, schematic view of the loxp-tagged Ghr allele (Ghrfl; Ghrtm1.1Masp) after excision of the neo cassette by Flp recombinase. Subsequent Cre-mediated excision of loxp sites produces the exon 4-deleted Ghr allele, Ghrtm1.2Masp. | ||||||
| Copyright | This image is from Fan Y, J Biol Chem 2009 Jul 24;284(30):19937-44 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:152627 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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