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Molecular Image Detail
Image
Caption Generation of the Igh-7tm1Lcwu allele. (A) Targeting scheme for insertion of human M1' and a bicistronic GFP reporter gene in the mouse IgE locus. Human M1' (red) is inserted into the mouse M1 exon splice acceptor site in-frame, with the M1 exon coding sequence. An IRES-GFP (green) bicistronic reporter gene is inserted 26-bases downstream of the end of the M2 exon.
Copyright This image is from Brightbill HD, J Clin Invest 2010 Jun 1;120(6):2218-29 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:161452
Associated
Alleles
Symbol Name
Igh-7tm1Lcwu immunoglobulin heavy chain 7 (heavy chain of IgE); targeted mutation 1, Lawren C Wu

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory