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| Caption | Generation of the Notch1tm4(cre)Rko allele. (A) Illustration of the gene targeting scheme. The three modifications introduced into this new line are labeled in red, including (1) removal of the 6xmyc tag; (2) the addition of an extra SV40 polyadenylation signal; (3) the C5178A silent substitution in Exon 28. | ||||
| Copyright | This image is from Liu Z, J Clin Invest 2011 Feb 1;121(2):800-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171829 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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