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| Caption | Generation of the Stab2tm1.1Cger allele. (A) Structural organization of the Stabilin-2 wild-type, knockout vector targeted, and Stab2tm1.1Cger (Stabilin-2 knockout) allele. The 2 loxP sites flanking exon 1 (red) are shown in green bars. The relative positions of probe-B used for Southern blot analysis and restriction endonuclease sites relevant for cloning procedures indicated as ERI (EcoRI), Sp (SpeI) K (KpnI), Nc (NcoI), Sph (SphI), H III (HindIII), S (SmaI), Xho (XhoI) are indicated. Cre-mediated deletion of exon 1 was achieved by crossing heterozygous floxed mice with C57BL/6 cre-deleter expressing constitutively recombinase cre, resulting in the Stab2tm1.1Cger allele. | ||||
| Copyright | This image is from Schledzewski K, J Clin Invest 2011 Feb 1;121(2):703-14 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171818 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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