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| Caption | Generation of the Ccr6tm1.1Jmf allele. (A) Targeting strategy. Schematic representation of the Ccr6 gene corresponding to positions 73,2125-73,8664 in GenBank record NT_039638 (and shown with numbering 1-6539 for this BamHI fragment, top panel), the pPNT-Ccr6 targeting vector (middle panel), and the disrupted/deleted Ccr6 gene (bottom panel). Hatched regions on the diagrams indicate the predicted ORF for Ccr6. Positions 3094-3611 in the ORF were deleted in targeted allele and a BamHI site was introduced at the 3' end of the 5' Ccr6 fragment. The location of the 5' probe used for analyzing DNA for the presence of the disrupted/deleted Ccr6 allele is indicated ("probe"). | ||||
| Copyright | This image is from Hedrick MN, J Clin Invest 2009 Aug;119(8):2317-29 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:152716 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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