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Image
Caption Generation of the Cryba1tm1a(EUCOMM)Hmgu allele. Schematic of the first knockout strategy used for generating knock-out mice. Shown is the Cryba1tm1a(EUCOMM)Hmgu knockout first allele with a (FRT)-flanked selection cassette inserted into the third intron of the Cryba1 (BetaA3/A1) gene, which traps the transcript through the Engrailed-2-splice acceptor (En2 sA) and truncates it through the SV40 polyadenylation signal. Primer specific to the neomycin resistance gene was used to confirm the disruption of the gene.
Copyright This image is from Hegde S, PLoS One 2016;11(2):e0149027, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:235696
Associated
Alleles
Symbol Name
Cryba1tm1a(EUCOMM)Hmgu crystallin, beta A1; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Cryba1tm1a(EUCOMM)Hmgu crystallin, beta A1; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory