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| Caption | Generation of the Hoxc8 replaced by Hoxc9 mouse alleles, Hoxc8tm3(Hoxc9)Jepl and Hoxc8tm4(Hoxc9)Jepl. (a) Hoxc8 genomic locus. E1 and E2 represent Exon1 and 2, yellow boxes represent coding region, purple lines represent the intron, and pink boxes represent the 3' untranslated region (UTR). X = Xba1, H = HindIII, Sp = Sph1, Sc = SacII, N = Nco1, Sl = Sal1, Ea = Ear1. Targeting constructs contain ~9.5-kb genomic DNA from the 5' Sph1 site to the 3' Xba1 site. "IR" represents internal ribosome reentry site, "marker" represents either eGFP or nlsLacZ reporters used in various versions of the targeting constructs. | ||||||
| Copyright | This image is from Blackburn J, Genesis 2009 Jul 20;47(10):680-687, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:153560 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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