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Molecular Image Detail
Image
Caption Generation of the Nr1h3tm1Wexi allele. A, depicted is the gene targeting strategy that was used to replace the endogenous Nr1h3 (LXRalpha) gene with VP-LXRalpha. Part of exon 2, exons 3-7, and introns in between of the wild-type allele were replaced by the VP-LXRalpha-SV40-Neo cassette. The Southern blot probe and prediction of NcoI restriction fragment sizes are labeled.
Copyright This image is from Gong H, J Biol Chem 2009 Oct 30;284(44):30113-21 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:155709
Associated
Alleles
Symbol Name
Nr1h3tm1Wexi nuclear receptor subfamily 1, group H, member 3; targeted mutation 1, Wen Xie

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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory