| Image |
|
||||||
| Caption | Generation of the Gdf11tm2.1Sjl and Gdf11tm2.2Sjl alleles. (A) Representation of targeting strategy. The 3 exons are shown as boxes with coding sequences shaded black and the 3'UTR open. The targeting construct is represented by a thick line which contains loxP sequences with EcoRI restriction sites inserted into the second XbaI site in exon 1 and flanking a neo gene inserted into the EcoRI site downstream of the 3'UTR. Cre-mediated recombination of the loxP sites flanking the neo gene results in a Gdf11tm2.1Sjl (Gdf11flox) allele. Recombination of the Gdf11tm2.1Sjl (Gdf11 flox allele) allele generates the Gdf11tm2.2Sjl (Gdf11 delta2-3 allele) allele. Oligonucleotide primers used for distinguishing alleles are labeled a, b, and c. | ||||||
| Copyright | This image is from McPherron AC, BMC Dev Biol 2009;9():24, an open-access article, licensee BioMed Central Ltd. J:158173 | ||||||
|
Associated Alleles |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/10/2024 MGI 6.24 |
|
|
|
||
Analysis Tools