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| Caption | (A) The strategy used to generate the Gorasp2tm1.1Maal allele is shown. The endogenous Gorasp2 locus contains 13 exons (only 6 represented black boxes) and introns (black lines). The targeting vector contained a diphtheria toxin A-negative selection cassette (DTA) followed by Gorasp2 sequences (exon 3 to exon 6) flanked by LoxP recombination sites (green) and a neomycin-positive selection cassette (NeoR) flanked by FLP recombination target (FRT) sites (blue). The recombined locus was obtained by homologous recombination. F1 breeding with CMV-Cre deleter mice resulted in knock-out of the Gorasp2 locus by Cre recombination (dashed black lines). The hybridization sites, PCR primer names and amplified fragment sizes are indicated in red. | ||||
| Copyright | This image is from Cartier-Michaud A, PLoS Genet 2017 Jun;13(6):e1006803, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:241919 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/17/2024 MGI 6.24 |
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